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Nikon

NIKKOR Z 100-400mm f/4.5-5.6 VR S

Nikon Z Mount

NIKKOR Z 100-400mm f/4.5-5.6 VR S — 100–400mm f/4.5-5.6 for Nikon Z, a popular choice in the nikon lineup.

$2,699

Launch price

Released Dec 2021

vs

Nikon

NIKKOR Z 50mm f/1.2 S

Nikon Z Mount

NIKKOR Z 50mm f/1.2 S — 50mm f/1.2 for Nikon Z, a popular choice in the nikon lineup.

$2,099

Launch price

Released Dec 2020

NIKKOR Z 100-400mm f/4.5-5.6 VR S is 1 year newer.

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Wins

2categories

NIKKOR Z 100-400mm f/4.5-5.6 VR S

WildlifeVideo & Hybrid

Wins

5categories

NIKKOR Z 50mm f/1.2 S

PortraitSports & Action

1 categories tied

TL;DR — Key differences

NIKKOR Z 100-400mm f/4.5-5.6 VR S wins 2 categories·NIKKOR Z 50mm f/1.2 S wins 3 categories
  • ANIKKOR Z 100-400mm f/4.5-5.6 VR S has higher OIS effectiveness (5 stops vs 0 stops)
  • BNIKKOR Z 50mm f/1.2 S has lower Max aperture (Tele) (f/1.2 vs f/5.6)
  • BNIKKOR Z 50mm f/1.2 S has lower Max aperture (Wide) (f/1.2 vs f/4.5)
  • ANIKKOR Z 100-400mm f/4.5-5.6 VR S has higher Max magnification (0.25 × vs 0.15 ×)
  • BNIKKOR Z 50mm f/1.2 S has lower Weight (1090 g vs 1435 g)

Key specs at a glance

NIKKOR Z 100-400mm f/4.5-5.6 VR SNIKKOR Z 50mm f/1.2 S
Focal Length100-400 mm50 mm
Max Aperturef/4.5-5.6f/1.2
MountNikon ZNikon Z
CoverageFull FrameFull Frame
Stabilization5 stopsNo
Weight1435 g1090 g
Min Focus38 cm30 cm
Filter Size77 mm77 mm

Use-case scoring

Which one for what?

Algorithmic scores from verified specs · 10 = best in class

Use caseNIKKOR Z 100-400mm f/4.5-5.6 VR SNIKKOR Z 50mm f/1.2 S
Portrait
5.5Fair
9.0Excellent
Sports & Action
6.5Good
6.5Good
Video & Hybrid
7.0Good
4.5Fair
Landscape
3.0Limited
4.0Fair
Travel
5.0Fair
2.0Limited
Wildlife
9.5Excellent
3.0Limited
Macro & Close-up
3.5Limited
1.5Limited

Why pick one over the other

Reasons to choose the NIKKOR Z 100-400mm f/4.5-5.6 VR S

  • OIS effectiveness

    5 stops vs 0 stops — higher is better

  • Optical stabilization

    Only NIKKOR Z 100-400mm f/4.5-5.6 VR S supports it

  • Max magnification

    0.25 × vs 0.15 × — higher is better

Reasons to choose the NIKKOR Z 50mm f/1.2 S

  • Max aperture (Tele)

    f/1.2 vs f/5.6 — lower is better

  • Max aperture (Wide)

    f/1.2 vs f/4.5 — lower is better

  • Special elements

    Adds ED

  • Weight

    1090 g vs 1435 g — lower is better

  • Min focus distance

    30 cm vs 38 cm — lower is better

  • Length

    203 mm vs 251 mm — lower is better

Shared specifications

Internal focus

Both support internal focus

Diameter

Both 81 mm

Weather sealing

Both support weather sealing

Control ring

Both support control ring

Custom function button

Both support custom function button

Pros & cons at a glance

Editorially curated highlights and trade-offs.

NIKKOR Z 100-400mm f/4.5-5.6 VR S

Pros

  • Versatile zoom range covers multiple focal lengths in one lens
  • Built-in optical image stabilization
  • Weather-sealed construction for outdoor shooting

Cons

  • Premium price point
  • Relatively heavy for extended handheld use
  • Slower maximum aperture limits low-light performance

NIKKOR Z 50mm f/1.2 S

Pros

  • Bright f/1.2 aperture for low light and subject separation
  • Prime design typically delivers strong sharpness and lighter weight
  • Weather-sealed construction for outdoor shooting

Cons

  • Premium price point
  • Relatively heavy for extended handheld use

Decided which one is right for you?

Compare live prices for the NIKKOR Z 100-400mm f/4.5-5.6 VR S and NIKKOR Z 50mm f/1.2 S at major authorized retailers.

Nikon NIKKOR Z 100-400mm f/4.5-5.6 VR S

Nikon NIKKOR Z 50mm f/1.2 S

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Full specifications

= category winner

NIKKOR Z 100-400mm f/4.5-5.6 VR S
NIKKOR Z 50mm f/1.2 S
Focal length (Min)
100 mm
50 mm
Focal length (Max)
400 mm
50 mm
Max aperture (Wide)
f/4.5
f/1.2+3.8 stops wider
Max aperture (Tele)
f/5.6
f/1.2+4.4 stops wider
Elements
23
14
Groups
17
11
Special elements
Aspherical
Aspherical, ED
NIKKOR Z 100-400mm f/4.5-5.6 VR S
NIKKOR Z 50mm f/1.2 S
Min focus distance
38 cm
30 cm−8 cm less
Max magnification
0.25 ×+67%
0.15 ×
Autofocus motor
Linear / Stepping Motor
Linear / Stepping Motor
Internal focus
Yes
Yes
NIKKOR Z 100-400mm f/4.5-5.6 VR S
NIKKOR Z 50mm f/1.2 S
Optical stabilization
Yes
No
OIS effectiveness
5 stops
0 stops
NIKKOR Z 100-400mm f/4.5-5.6 VR S
NIKKOR Z 50mm f/1.2 S
Weight
1435 g
1090 g−345 g less
Length
251 mm
203 mm−48 mm less
Diameter
81 mm
81 mm
Filter thread size
77 mm
77 mm
Weather sealing
Yes
Yes
Diaphragm blades
9
11
NIKKOR Z 100-400mm f/4.5-5.6 VR S
NIKKOR Z 50mm f/1.2 S
Lens mount
Nikon Z
Nikon Z
Format coverage
Full Frame
Full Frame

Specs sourced from manufacturer data. Use-case scores algorithmically derived. Last reviewed May 2026.