Fujifilm
GFX100S II
Compact 102MP GFX medium format body with X-Processor 5, 8-stop IBIS, and updated subject detection.
$4,999
Launch priceReleased May 2024
Pentax
645Z
51MP medium format DSLR that made digital MF accessible — still prized for landscape and studio.
$8,499
Launch priceReleased Apr 2014
GFX100S II is 10.1 years newer.
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Wins
GFX100S II
Wins
645Z
3 categories tied
Which would you choose?
TL;DR — Key differences
- B645Z has higher Burst (electronic) (20 fps vs 4.1 fps)
- AGFX100S II has higher Max video bit rate (720 Mbps vs 150 Mbps)
- AGFX100S II has higher AF points / zones (425 vs 101)
- B645Z has higher ISO max (native) (25,600 vs 12,800)
- B645Z has higher 4K max frame rate (60 fps vs 30 fps)
Key specs at a glance
Size and weight, to scale
📸 Snap this size diff to shareGFX100S II
150 × 104 × 87 mm
883 g (1.95 lb / 31.15 oz)
Credit card
85.6 × 54 mm
for scale
645Z
156 × 117 × 123 mm
1470 g (3.24 lb / 51.85 oz)
GFX100S II is 6mm narrower, 13mm shorter, and 36mm thinner than 645Z.
GFX100S II is 587 g lighter than 645Z.
Depth (front-to-back): 87mm GFX100S II · 123mm 645Z
Sensor size, to scale
GFX100S II
43.8 × 32.9 mm · Medium Format
1441 mm² area
645Z
43.8 × 32.8 mm · Medium Format
1437 mm² area
Use-case scoring
Which one for what?
Algorithmic scores from verified specs · 10 = best in class
Why pick one over the other
Reasons to choose
GFX100S II
Dimensions (W×H×D mm)
Adds 150, 104.2, 87.2
Max video bit rate
720 Mbps vs 150 Mbps — higher is better
AF points / zones
425 vs 101 — higher is better
Subject recognition
Adds Automobile, Motorcycle/Bike, Airplane…
Card types
Adds SDXC V90, SSD via USB
Codecs
Adds Apple ProRes 422 HQ, Apple ProRes 422, Apple ProRes 422 LT
Internal RAW video
Only GFX100S II supports it
Resolution
102 MP vs 51.4 MP — higher is better
Reasons to choose
645Z
Dimensions (W×H×D mm)
Adds 156, 117, 123
Burst (electronic)
20 fps vs 4.1 fps — higher is better
AA filter
Only 645Z supports it
ISO max (native)
25,600 vs 12,800 — higher is better
Subject recognition
Adds Human, Vehicle
Pre-Capture / Pre-Release
Only 645Z supports it
4K max frame rate
60 fps vs 30 fps — higher is better
ISO min (native)
64 vs 80 — lower is better
Both cameras share
- ✓AF frame coverage — Both 100 %
- ✓Eye AF — Both support eye af
- ✓Animal / bird AF — Both support animal / bird af
- ✓In-body stabilization (IBIS) — Both support in-body stabilization (ibis)
- ✓Weather sealing — Both support weather sealing
- ✓Card slots — Both 2
Pros & cons at a glance
Editorially curated highlights and trade-offs.
GFX100S II
Pros
- ✓102MP medium format sensor
- ✓8-stop IBIS
- ✓X-Processor 5
- ✓Compact for GFX
Cons
- –Large files
- –Premium price
- –Medium format AF not for sports
645Z
Pros
- ✓51MP medium format
- ✓CMOS sensor
- ✓Pentax color
- ✓Relatively affordable MF
Cons
- –Huge body
- –Slow operation
- –Limited lens line vs Hasselblad
Decided which one is right for you?
Compare live prices for the GFX100S II and 645Z at major authorized retailers.
Fujifilm GFX100S II
Pentax 645Z
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Full specifications
✓ = category winner
Frequently asked
Quick answers generated from verified specs.
Which is better for wildlife, GFX100S II or 645Z?
645Z scores 9.0/10 versus 5.0/10 for GFX100S II — 20fps burst captures fleeting moments.
What's the resolution difference between the GFX100S II and 645Z?
GFX100S II is 102 MP and 645Z is 51.4 MP, so the GFX100S II captures more detail for cropping and large prints.
Do the GFX100S II and 645Z have in-body image stabilization?
GFX100S II has 8-stop in-body image stabilization, while 645Z has 7-stop in-body image stabilization.
Which shoots faster bursts — the GFX100S II or the 645Z?
GFX100S II reaches 7 fps mechanical. 645Z reaches 20 fps electronic.
What's the weight difference between the GFX100S II and 645Z?
GFX100S II weighs 883 g and 645Z weighs 1470 g, so the GFX100S II is 587 g lighter.
Do the GFX100S II and 645Z record 4K video?
GFX100S II: 4K up to 30p. 645Z: 4K up to 60p.
Are the GFX100S II and 645Z weather sealed?
GFX100S II: Yes. 645Z: Yes.
Which has better battery life?
Rated battery life is 530 shots (CIPA) for the GFX100S II and 640 shots for the 645Z, giving the 645Z the edge.
How much does each cost?
GFX100S II launched at $4,999 and 645Z at $8,499. The GFX100S II is $3,500 less.
Can't decide between two? Compare a third camera.
Add any camera to get a three-way GFX100S II vs 645Z vs X comparison.
Specs sourced from manufacturer data. Use-case scores algorithmically derived. Last reviewed June 2026.