Canon
EOS R6 Mark II
Versatile 24.2MP full-frame hybrid with class-leading AF and 4K 60p video.
$2,499
Launch priceReleased Nov 2022
Pentax
645Z
51MP medium format DSLR that made digital MF accessible — still prized for landscape and studio.
$8,499
Launch priceReleased Apr 2014
EOS R6 Mark II is 8.6 years newer.
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Wins
EOS R6 Mark II
Wins
645Z
5 categories tied
Which would you choose?
TL;DR — Key differences
- AEOS R6 Mark II has higher AF points / zones (1053 vs 101)
- AEOS R6 Mark II has higher ISO max (native) (102,400 vs 25,600)
- AEOS R6 Mark II has higher Max video bit rate (340 Mbps vs 150 Mbps)
- AEOS R6 Mark II has lower Weight (670 g vs 1470 g)
- B645Z has higher Resolution (51.4 MP vs 24.2 MP)
Key specs at a glance
Size and weight, to scale
📸 Snap this size diff to share
EOS R6 Mark II
138 × 98 × 88 mm
670 g (1.48 lb / 23.63 oz)
Credit card
85.6 × 54 mm
for scale
645Z
156 × 117 × 123 mm
1470 g (3.24 lb / 51.85 oz)
EOS R6 Mark II is 18mm narrower, 19mm shorter, and 35mm thinner than 645Z.
EOS R6 Mark II is 800 g lighter than 645Z.
Depth (front-to-back): 88mm EOS R6 Mark II · 123mm 645Z
Back view, to scale
Width × Height — same proportions as the front of the body.
EOS R6 Mark II
138 × 98 mm
Credit card
85.6 × 54 mm
645Z
156 × 117 mm
Top view, to scale
Width × Depth (front-to-back) — see which body is chunkier on the table.
EOS R6 Mark II
138 × 88 mm
Credit card
85.6 × 54 mm
645Z
156 × 123 mm
Sensor size, to scale
EOS R6 Mark II
35.9 × 23.9 mm · Full Frame
858 mm² area
645Z
43.8 × 32.8 mm · Medium Format
1437 mm² area
1.7× larger sensor area = shallower depth of field and better low-light performance.
Lens ecosystem
Native lens selection
EOS R6 Mark II
✓ more lensesCanon RF
105+
native lenses available
645Z: mount data unavailable
Counts include current first-party and major third-party native autofocus lenses.
Use-case scoring
Which one for what?
Algorithmic scores from verified specs · 10 = best in class
Why pick one over the other
Reasons to choose
EOS R6 Mark II
AF low-light limit
-6.5 EV vs -3 EV — lower is better
Subject recognition
Adds People, Dogs, Cats…
Dimensions (W×H×D mm)
Adds 138.4, 98.4, 88.4
AF points / zones
1053 vs 101 — higher is better
ISO max (native)
102,400 vs 25,600 — higher is better
Max video bit rate
340 Mbps vs 150 Mbps — higher is better
Weight
670 g vs 1470 g — lower is better
Burst (electronic)
40 fps vs 20 fps — higher is better
Reasons to choose
645Z
Subject recognition
Adds Human, Animal, Bird…
Dimensions (W×H×D mm)
Adds 156, 117, 123
Resolution
51.4 MP vs 24.2 MP — higher is better
ISO min (native)
64 vs 100 — lower is better
EVF magnification
0.78 × vs 0.76 × — higher is better
Both cameras share
- ✓AA filter — Both support aa filter
- ✓AF frame coverage — Both 100 %
- ✓Eye AF — Both support eye af
- ✓Animal / bird AF — Both support animal / bird af
- ✓Pre-Capture / Pre-Release — Both support pre-capture / pre-release
- ✓4K max frame rate — Both 60 fps
Pros & cons at a glance
Editorially curated highlights and trade-offs.
EOS R6 Mark II
Pros
- ✓Up to 40fps electronic burst
- ✓4K 60p oversampled from 6K
- ✓Dual Pixel CMOS AF II — superb subject tracking
- ✓8-stop IBIS
- ✓Fully articulating touchscreen
Cons
- –24.2MP may feel limiting for large prints
- –No CFexpress on base body
- –Short battery life vs. A7 IV
645Z
Pros
- ✓51MP medium format
- ✓CMOS sensor
- ✓Pentax color
- ✓Relatively affordable MF
Cons
- –Huge body
- –Slow operation
- –Limited lens line vs Hasselblad
Decided which one is right for you?
Compare live prices for the EOS R6 Mark II and 645Z at major authorized retailers.
Canon EOS R6 Mark II
Pentax 645Z
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Full specifications
✓ = category winner
Frequently asked
Quick answers generated from verified specs.
Which is better for portraits, EOS R6 Mark II or 645Z?
EOS R6 Mark II scores 8.5/10 versus 6.0/10 for 645Z — 24.2MP — solid resolution.
What's the resolution difference between the EOS R6 Mark II and 645Z?
EOS R6 Mark II is 24.2 MP and 645Z is 51.4 MP, so the 645Z captures more detail for cropping and large prints.
Do the EOS R6 Mark II and 645Z have in-body image stabilization?
EOS R6 Mark II has 8-stop in-body image stabilization, while 645Z has 7-stop in-body image stabilization.
Which shoots faster bursts — the EOS R6 Mark II or the 645Z?
EOS R6 Mark II reaches 40 fps electronic. 645Z reaches 20 fps electronic.
What's the weight difference between the EOS R6 Mark II and 645Z?
EOS R6 Mark II weighs 670 g and 645Z weighs 1470 g, so the EOS R6 Mark II is 800 g lighter.
Do the EOS R6 Mark II and 645Z record 4K video?
EOS R6 Mark II: 4K up to 60p. 645Z: 4K up to 60p.
Are the EOS R6 Mark II and 645Z weather sealed?
EOS R6 Mark II: Yes. 645Z: Yes.
Which has better battery life?
Rated battery life is 760 shots (CIPA) for the EOS R6 Mark II and 640 shots for the 645Z, giving the EOS R6 Mark II the edge.
How much does each cost?
EOS R6 Mark II launched at $2,499 and 645Z at $8,499. The EOS R6 Mark II is $6,000 less.
Can't decide between two? Compare a third camera.
Add any camera to get a three-way EOS R6 Mark II vs 645Z vs X comparison.
Specs sourced from manufacturer data. Use-case scores algorithmically derived. Last reviewed June 2026.
Product images courtesy of Canon and Pentax press materials.